ADM has published research in the journal Animals showing its PRIOME Oral Care postbiotic significantly reduced dental plaque accumulation in dogs. The randomized, blinded, placebo-controlled clinical trial involved 60 healthy adult dogs over 57 days.
Following dental cleaning, researchers divided the dogs into three groups receiving either a placebo or low- or high-dose PRIOME Oral Care mixed with dry kibble. The team assessed dental plaque, gum health, bad breath and tartar at regular intervals and conducted microbiome analysis.
Dogs receiving the high dose showed a 10% reduction in dental plaque accumulation between day 29 and day 57. The low-dose group demonstrated an overall trend toward reduced plaque formation compared to placebo. Microbiome analysis indicated the postbiotic may support overall oral health.
"Maintaining good oral hygiene in dogs is important to their overall wellness and it's a growing concern among pet owners, yet regular toothbrushing can be challenging," said Dr. Sophie Nixon, head of R&D Clinical Research for Pet & Animal Wellbeing, ADM. "Our research highlights the potential for innovative postbiotic solutions to help support canine oral care and represents a promising step forward in identifying more convenient approaches to supporting oral health."
The study represents the first canine clinical trial examining PRIOME Oral Care's effects on dental plaque formation and oral microbiome support in dogs.
"This scientific publication is the culmination of many years of research and development work, spanning multiple ADM teams, sites and countries, and details the full process of strain identification, pre-clinical characterization and clinical substantiation," said Peter Jüsten, global vice president, R&D Health & Wellness at ADM. "In addition, it contributes to an expanding body of scientific evidence supporting the role of postbiotics in reinforcing pet wellness."
The postbiotic is derived from Lactiplantibacillus plantarum CECT 9161 strain in heat-treated form. ADM's Research and Development team conducted the trial to evaluate the ingredient's potential for inclusion in pet food formulations targeting oral health.
