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DSM-Firmenich urges caution when sourcing 25OHD3 ingredients

New standard introduced by the China Feed Industry Association may mean that existing products containing calcitriol impurities, now discouraged in China, may be diverted to export markets.

DSM-Firmenich is urging ingredient buyers and feed manufacturers to exercise caution when sourcing 25-hydroxyvitamin D3 (25OHD3) feed ingredients in the coming months, after a major regulatory shift in China. 

The China Feed Industry Association (CFIA) recently introduced a landmark feed group standard on the sale and use of any 25OHD3 feed additives containing detectable levels of 1α,25-dihydroxycholecalciferol (calcitriol) within China. 

This move marks a major step forward in feed safety, traceability and quality control, but it also carries global implications for feed and animal nutrition markets, DSM-Firmenich said. 

The new guidance also means that existing products containing calcitriol impurities, now discouraged in China, may be diverted to export markets. Experts warn that 25OHD3 products containing 1α,25-dihydroxycholecalciferol could easily enter circulation in other countries with less stringent regulations or enforcement. 

“China’s new feed standard is a significant step forward for China and global feed safety and quality assurance,” said José María Hernández, global special nutrients ANH, DSM-Firmenich. “It highlights the importance of knowing exactly what’s in your vitamin supply and choosing sources you can trust. Now more than ever, buyers everywhere should consider to prioritize reliable, high-quality and globally registered 25OHD3 sources with proven safety and efficacy.” 

Feed manufacturers, nutritionists, and integrators are encouraged to: 

  • Verify supplier compliance of products manufactured in China with the latest CFIA and international standards.
  • Request analytical certificates confirming “not detectable” levels of calcitriol.
  • Prioritize trusted, globally registered 25OHD3 sources with proven safety and efficacy track records.
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