New genotype of H5N1 virus found in Nevada dairy cattle

Confirmed by whole genome sequence by the National Veterinary Services Laboratories, this is the first detection of H5N1 clade 2.3.4.4b, genotype D1.1 in dairy cattle. All previous detections in dairy cattle have been H5N1 clade 2.3.4.4b, genotype B3.13.

February 6, 2025

H5 N1

JegasRa | BigStock.com

A new genotype of the H5N1 virus has been confirmed in dairy cattle in Nevada, according to the U.S. Department of Agriculture (USDA) Animal and Plant Health Inspection Service (APHIS).

Confirmed by whole genome sequence by the National Veterinary Services Laboratories (NVSL), this is the first detection of H5N1 clade 2.3.4.4b, genotype D1.1 in dairy cattle. All previous detections in dairy cattle have been H5N1 clade 2.3.4.4b, genotype B3.13. Genotype D1.1 represents the predominant genotype in the North American flyways last fall and this winter and has been identified in wild birds, mammals and spillovers into domestic poultry.

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