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Edema disease remains a complicated disorder that perplexes nutritionists and veterinarians today as it did more than 10 years ago, when I wrote my first article on the topic. Given a recent outbreak of edema disease in a client’s farm, I had to revisit this topic and update my knowledge. Today, as it was back then, nutrition can play a dual role in either preventing the occurrence or alleviating the symptoms of the disease once it happens. In my experience, prevention works best.